E241: What is the connection between the gut and our brain?

August 13, 2024

We’ve recorded a series of podcasts on the microbiome and its wide ranging impacts. But boy is this a field that moves rapidly. As soon as you think you’ve covered much of the territory, along comes some new and exciting findings, and this is the case today. We’re going to describe research done by our guest, Dr. Ibrahim Javed. He has done innovative work on links between the gut microbiome and the brain, particularly focused on Alzheimer’s disease. Dr. Javed is an Enterprise Fellow and National Health and Medicine Research Council Emerging Leadership Fellow in Clinical and Health Sciences at the University of South Australia.

Related podcasts: Child Development & Nutrition | Diet & Nutrition | Microbiome |

 

E217: When babies inherit Mom’s trauma-affected gut microbiome

October 12, 2023

A diversity of bacteria and microorganisms making up the gut microbiome supports both our physical and our mental health. Research has shown that stress and trauma can negatively impact the microbiome. But a recent study took that finding to a new level. This was a study published in the Proceedings of the National Academy of Sciences. Scientists now see inflammation-related microbiomes in babies born to women who experienced mistreatment or adversity during their own childhood. These microbiomes predispose children to physical and mental health problems. We’ll talk today with the co-author of that paper, Fran Querdasi, from the University of California, Los Angeles.

Related podcasts: Child Development & Nutrition | Diet & Nutrition | Food, Psychology & Neuroscience | Microbiome |

 

E210: Clinical Trial Evidence: Metabolic Effect of Sweeteners

July 24, 2023

Sugar replacements, known generally as artificial sweeteners or non-nutritive sweeteners, have been in the news a lot. Rising concerns exist about safety and the effects of the sweeteners on many key features of health, including the microbiome. We need the help of talented scientists to sort through this complex web of information. Today’s guest, Professor Eran Elinav, has done some of the seminal research in this area. He’s an expert on systems immunology at the Weizmann Institute of Science in Israel.

Related podcasts: Diet & Nutrition | Food Policy | Food Safety & Food Defense | Microbiome | Zero Calorie Sweeteners |

 

E209: Microbiome Research and a Vision of Precision Medicine

July 13, 2023

The microbiome is fascinating and how diet affects it is something we all want to know. The work of today’s guest, Dr. Abigail Johnson, tells us a lot. She’s on the faculty and the School of Public Health at the University of Minnesota and is an expert on diet and the microbiome and their impact on health and disease.

Related podcasts: Diet & Nutrition | Food, Psychology & Neuroscience | Microbiome |

 

E208: Improve Your Microbiome – Improve Your Health

July 6, 2023

If you want to improve your digestion, your immune system, and your overall health, one might begin with a focus on a healthy gut microbiome. Today we’re talking with Stanford University professor of microbiology and immunology Dr. Justin Sonnenburg, co-author of the book entitled, “The Good Gut: Taking Control of Your Weight, your Mood, and Your Long-Term Health.” He and his wife, research scientists Dr. Erica Sonnenburg, argue that our typical modern diet has caused the microbial diversity or intestine to shrink substantially. Turns out that’s a big problem.

Related podcasts: Diet & Nutrition | Microbiome | Ultra-processed Food & Additives |

 

E207: World Health Organization’s Recommendations on Non-Sugar Sweeteners

June 28, 2023

Today’s podcast is a continuation of our series exploring the safety of non-sugar sweeteners in both food and beverages. In 2022, the World Health Organization conducted a systematic review of the most current scientific evidence on the health effects of non-sugar sweeteners. This analysis of 283 studies reveals that non-sugar sweeteners can impact health conditions such as cardiovascular disease, type 2 diabetes, adiposity, bladder cancer, and preterm birth. In 2023, the WHO released a guideline on the use of non-sugar sweeteners based on this 2022 review. Our guests today are Dr. Jason Montez, scientist with the World Health Organization, and technical lead on the systematic review and guideline. And, the director of the Department of Nutrition and Food Safety at the World Health Organization, Dr. Francesco Branca.

Related podcasts: Childhood Obesity | Diet & Nutrition | Food Policy | Food Safety & Food Defense | Microbiome | Obesity | Zero Calorie Sweeteners |

 

E205: Here’s what sugar and zero-calorie sweeteners do to your body

May 17, 2023

Today we speak with an expert on sugar and things meant to replace it. The stakes are high. Very high. Sugar consumption in the population is astronomical and so is the use of sugar replacements. Knowing the impacts of both could help experts provide dietary guidance and help consumers make decisions. Dr. Robert Lustig is Professor Emeritus of Pediatrics in the Division of Endocrinology at the University of California, San Francisco. He specializes on the regulation of energy balance by the central nervous system; body weight regulation, appetite, metabolism, and is very well known for his work on sugar and their substitutes and on policies aimed at improving the diet of the population. A YouTube video on the effects of consuming sugar called “Sugar: The Bitter Truth,” has now been viewed 24 million times.

Related podcasts: Addiction & Food | Diet & Nutrition | Food Industry Behavior & Marketing | Food Safety & Food Defense | Microbiome | Zero Calorie Sweeteners |

 

E204: The troubling unknowns of non-caloric sweeteners

May 4, 2023

As a society, we are eating and drinking low-calorie sweeteners more and more. Researchers are working to understand the long-term impact of such sweeteners for adults and, of course, for children. This interview is part of a series on the impact of sweeteners. Our guest today is Dr. Allison Sylvetsky, Associate Professor in the Department of Exercise and Nutrition Sciences at the George Washington University – Milken Institute School of Public Health.

Related podcasts: Child Development & Nutrition | Diet & Nutrition | Food Safety & Food Defense | Microbiome | Ultra-processed Food & Additives | Zero Calorie Sweeteners |

 

E202: Impact of non-caloric sweeteners on the microbiome – what we know now

April 13, 2023

With the widespread presence of artificial sweeteners in the food system, scientists and consumers want to know about their safety. Safety concerns have been expressed for years, and lots of research has been done, but relatively new on the scene is work examining the effect of sweeteners on the microbiome. This interview is part of a series on the impact of artificial sweeteners. Our guest today, Dr. Jotham Suez, is doing fascinating work on this topic. He’s Assistant Professor of Molecular Microbiology and Immunology and the Public Health Johns Hopkins University.

Related podcasts: Diet & Nutrition | Food Safety & Food Defense | Microbiome | Zero Calorie Sweeteners |

 

E115: How Precision Diet Might Overcome Some Genetic Roadblocks

February 18, 2021

Could there come a day when an optimal diet could be recommended not just for the population overall or for people with special conditions such as diabetes but a diet that would be unique for you? A diet based on your genetics let’s say on the condition of your microbiome perhaps? Or on your environmental exposures or other factors? This futuristic possibility may be closer than you think. Thanks to the work of researchers, including today’s guest Dr. Steven Zeisel, Director of the Nutrition Research Institute and Director of the Nutrition Obesity Research Center at the University of North Carolina.

Related podcasts: Diet & Nutrition | Microbiome |